I have Asperger's syndrome and have suffered from agoraphobia and depression for a decade. My family and friends slowly disappeared from the scene nine years ago. I have tried antidepressants, psychotherapy and psychiatric hospital admission to no avail. My partner's life has been blighted by this. He comes home from work to Groundhog Day – dishes unwashed, laundry undone, and me unbathed, unmoved, unbearable. I cannot bear what this is doing to him; he says he cannot bear what it is doing to me. Agoraphobia traps me indoors and precludes the use of public transport, shopping or being in crowds. Depression destroys my ability to use the phone, to talk to or be among others. I am childless and in my 30s. What do I do?

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