The nasty country

Madeleine Bunting: But are politicians to blame for Britain's social recession and can they put it right?

Support acts

Following a career crisis, Lindsay Swan put her initial scepticism to one side in order to find out whether professional coaching could really make her a happier, better worker

Biotech firm in cannabis breakthrough

9.45am: GW Pharmaceuticals today signed up Japan's Otsuka to develop and market its pioneering cannabis-based drug Sativex in the US. By Julia Kollewe.

Lost health, lost home, lost job – and no one to help

In 1993, Lee Burbidge was diagnosed with a rare cancer called musculoaponeurotic fibromatosis. He had six weeks of radiotherapy, then two years of physiotherapy after nerve damage led to the loss of the use of his arm. Lee's wife, Lynn, left her job to become his carer and, six months after the operation, they lost the business they had set up together.

Drugs giant warns on new heart treatment

8.15am: AstraZeneca has raised fresh fears over its threadbare drug development pipeline, admitting that its heart drug AGI-1067 is a 'very high-risk project'. By Julia Kollewe.